National Immunization Schedule (NIS) for Infants, Children and Pregnant Women

Vaccine When to give Dose Route Site
For Pregnant Women
TD-1 Early in pregnancy 0.5 ml Intra-muscular Upper Arm
TD-2 4 weeks after TT-1* 0.5 ml Intra-muscular Upper Arm
TD-Booster If received 2 TT doses in a pregnancy within the last 3 yrs* 0.5 ml Intra-muscular Upper Arm
For Infants
BCG At birth or as early as possible till one year of age 0.1ml (0.05 ml until 1 month age) Intra-dermal Left Upper Arm
Hepatitis B - Birth dose At birth or as early as possible within 24 hours 0.5 ml Intra-muscular Antero-lateral side of mid-thigh
OPV-0 At birth or as early as possible within the first 15 days 2 drops Oral Oral
OPV 1, 2 & 3 At 6 weeks, 10 weeks & 14 weeks (OPV can be given till 5 years of age) 2 drops Oral Oral
Pentavalent 1, 2 & 3 At 6 weeks, 10 weeks & 14 weeks (can be given till one year of age) 0.5 ml Intra-muscular Antero-lateral (left) side of mid-thigh
Rotavirus# At 6 weeks, 10 weeks & 14 weeks (can be given till one year of age) 2.5 ml Oral Oral
IPV Two fractional dose at 6 and 14 weeks of age 0.1 ml Intra dermal two fractional dose Intra-dermal: Right upper arm
PCV 1ST & 2ND Two fractional dose at 6 and 14 weeks of age 0.5 ml Intra dermal two fractional dose Antero Lateral side of mid thigh
MR 1st Dose$ 9 completed months-12 months (can be given till 5 years of age) 0.5 ml Sub-cutaneous Right upper Arm
PCV 3rd 9 completed months-12 months 0.5 ml Intra muscular Antero-lateral(R) side of mid-thigh
Vitamin A (1st dose) At 9 completed months with measles- Rubella 1 ml ( 1 lakh IU) Oral Oral
For Children
DPT booster-1 Vit A 2nd dose 16-24 months 0.5 ml 2 ml (2 lakh Unit) Intra-muscular Oral Antero-lateral side of mid-thigh
MR 2nd dose $ 16-24 months 0.5 ml Sub-cutaneous Right upper Arm
OPV Booster 16-24 months 2 drops Oral Oral
Vitamin A*** (3rd to 9th dose) 16-18 months. Then one dose every 6 months up to the age of 5 years 2 ml (2 lakh IU) Oral Oral
DPT Booster-2 5-6 years 0.5 ml Intra-muscular Upper Arm
TD 10 years & 16 years 0.5 ml Intra-muscular Upper Arm
  • *Give TT-2 or Booster doses before 36 weeks of pregnancy. However, give these even if more than 36 weeks have passed. Give TT to a woman in labour, if she has not previously received TT.
  • **JE Vaccine is introduced in select endemic districts after the campaign.
  • *** The 2nd to 9th doses of Vitamin A can be administered to children 1-5 years old during biannual rounds, in collaboration with ICDS.
  • #Phased introduction, at present in Andhra Pradesh, Haryana, Himachal Pradesh and Orissa from 2016 & expanded in Madhya Pradesh, Assam, Rajasthan, and Tripura in February 2017 and planned in Tamil Nadu & Uttar Pradesh in 2017.
  • $ Phased introduction, at present in five states namely Karnataka, Tamil Nadu, Goa, Lakshadweep and Puducherry. (As of Feb’ 2017)
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